Its all about water pressure. If you have low water pressure then throttling back the amount going to waste can help. But a lower water pressure than 50 psi will mean that the membrane won't quite work as efficiently as it would at a higher pressure. 50psi is the low end of the water pressure spectrum.
But in my expereience, my HF5 membrane is performing to spec so I personally can't see there being that much of a difference between 50 and 45psi. (If I have my r/o running and I turn on the outside tap the water pressure to the r/o will drop to around 40psi. Currently with a tap water tds of around 100 I've seen the output of my pure tds rise from 2 to 3ppm at 40 psi. For me the difference between the r/o working at 40psi and 50psi is negligible, for you it might mean the output difference of 3ppm. No one knows for sure.)
Your water tds is high at 320 so you might find your membranes longevity will suffer.
You just have to see if it works for you.
Nobody, and I mean nobody, will be able to tell you exactly how an HF5 membrane will work with your water pressure, your water temperature or the composition of the dissolved solids in your water.
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