I've got extremely sensitive skin, the big softy I am, and have ended up at the doctors two occasions with hands that looked like prunes.
There's various barrier creams you can buy. Boots do one; just keep re-applying it. But it didn't work for me.
There's also a spray that claims to act like a 'second skin', but it's about £20 for a small can - Handguard I think it's called; didn't work for me either!
Handguard:
http://homepages.acenet.co.za/handguard/Why%20Handguard.htmlIn the end I opted for a water-proof glove.
After trying lots of different gloves I find a cotton inner (from Boots) and a 'marigold' is the best.
However, I've just bought Wor Lass a pair of Seal Skinz and she thinks they're great. 100% waterproof, warm and provides good manual dexterity.
Link here to Sealskinz and Unger gloves:
http://www.soapnational.co.uk/acatalog/Gloves.htmlI may get a pair of sealskinz, but cotton inners and marigolds are fine for me. It's just a little bit of a pain putting on two sets of gloves!
PS.
If you opt for the 'marigold option', buy three lots of cotton inners, so that you can change them when they get wet from your sweat and wash them with your scrims.
Also Unger Gloves are okay (neoprene), but wear out easily with heavy duty use. I've heard them described as 'disposable gloves' here.