It is not cost-effective to separate a sealed unit to clean it and it would nearly always break if you attempted to do so.
You unclip the beading from the inside, take measurements (Height width depth) of the glass unit and order another. You go back and put them in. Put the spacers in so as they don't block the drainage holes.
If it's a door or goes to ground level it needs to be laminated.
Price is size dependent and so a top opener 600mm x 300mm might cost you (the installer) £50 where as a 1200 x 600 might be £100. You then add on a bit of profit and your time and charge accordingly.
I've done one in my own house (UPVC) but it is so easy to mark the plastic beads. And the measurements have to be accurate, obviously.