If you have pump before DI i.e - push water through it, try reversing this & let the pump pull water through it. keep the vessel direction the same (in/out has to be kept the same wether pushing or pulling). I find this puts far less stress on the pump & better for keeping air locks out. i had similar a while back, for some reason kept getting air lock in 1 of my DI's & resulting in no flow.
Tony