If you run parallel , assuming a waste ratio of 60% waste, 40% product for each RO membrane then thats still your final waste ratio, 60%. If you run in series at the same ratios, then you will be re using the 60% waste from the first RO, and 'wasting' 60% of that.
100 litres=40 litres product=60 litres waste, through another ro 60 litres waste will give you 24 litres product and 36 litres waste.
Total waste for 100 litres parallell = 60 litres.
Total waste for 100 litres series = 36 litres.